Improving the quality of life for breast cancer survivors using innovative 3D bio-printing with a woman’s own cells, to improve breast reconstruction results – starting with the nipple and later addressing other pigmentation and tissue deficit needs in the broad field of reconstruction.
Cancer affects us all.
Or will at some point.
The good news is that the odds of breast cancer survival are increasing. Women are finding breast cancer earlier than ever and beating it. This makes improvements in breast reconstruction techniques more important than ever.
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TeVido’s proprietary platform technology uses 3D bio-printing and a patient’s own living cells to build custom grafts that address significant unmet needs in the broad field of reconstructive and cosmetic surgery – where current fillers, fat injections and skin/tissue grafting results are unpredictable. The first product will improve nipple reconstruction, for breast cancer survivors, where current procedures flatten and fade over time. TeVido is privately held.
For the majority of women who undergo breast reconstruction, the final step in the process involves the nipple areola complex (NAC). Studies highlight that patients with loss of the nipple and areola continue to experience psychological distress even long after breast mound reconstruction has taken place and recreation of the nipple-areola complex has a high correlation with overall patient satisfaction and acceptance of body image. Most women who have reconstruction also opt for some type of NAC reconstruction. Unfortunately, results of currently available NAC reconstruction techniques are unpredictable. TeVido is developing propriety, patent-pending, bioprinting technology, CellatierTM, and when combined with a woman’s own living cells will build a custom NAC graft made just for her.
Globally, in 2010, nearly 1.5 million were told “you have breast cancer” and in the US in 2013 it is estimated to be more than 296,000; nearly 40% of women opt for mastectomy, or full removal of the breast tissue for their cancer treatment regime – of those 24% will have a double mastectomy, removing both breasts. Approximately 1/3 of mastectomy patients will decide to undergo breast reconstruction and women with double mastectomies have double the rates of reconstruction.
Longer term, as CellatierTM technology is matured, a second opportunity in breast reconstruction is to address the unmet challenge in filling lumpectomy voids. Approximately 60% of women will opt for lumpectomy treatment, of those, at least 25% are dissatisfied with the physical outcome of the remaining breast tissue and those women were far more likely to experience symptoms of depression and fear of cancer recurrence compared to women with minimal asymmetry. However few reconstructive options exist for lumpectomies. Women undergoing lumpectomies to remove tumors or breast cancer are faced with limited options if they are unhappy with the physical outcome of their breast: spend months filling the void with a series of fat injections, which then have the potential to be reabsorbed into the body; or do nothing, which can leave breasts disfigured and asymmetrical. An adjacent market exists for soft tissue reconstruction for other conditions such as sport and war related injuries resulting in tissue deficiency as well as the rare soft tissue sarcomas of the extremities. These conditions have significant quality of life impacts for the patient.
 Evans KK, Rasko Y, Lenert J. The use of calcium hydroxylapatite for nipple projection after failed nipple-areolar ] reconstruction: early results. Ann Plast Surg. Jul 2005;55(1):25-9; discussion 29. [cited Jan 2014] available from http://emedicine.medscape.com/article/1274411-overview
 Worldwide Breast Cancer, Breast Cancer Statistics Worldwide; [cited Jan 2014], available from http://www.worldwidebreastcancer.com/learn/breast-cancer-statistics-worldwide/
 American Cancer Society. Cancer Facts & Figures 2013. Atlanta. American Cancer Society, Inc
 Reconstructive Surgery Markets in Europe, ed. F. Sullivan. 2007.
 Gilbert, Allison, “Why more women are choosing double mastectomies”, CNN May 14,2013; [cited Feb 2013]; Available from http://www.cnn.com/2013/03/13/health/double-mastectomy-rates-up/
 Seamon, Andrew, “Better education on breast reconstruction may be needed after cancer”, GMA News/Reuters September 1, 2014; [cited October 2014]; Available from http://www.gmanetwork.com/news/story/377258/lifestyle/healthandwellness/better-education-on-breast-reconstruction-may-be-needed-after-cancer